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Necrotizing soft tissue infection of the upper leg as first presentation of necrotizing pancreatitis: a case report

Ahead of print available from 30/06/2022
These articles are scheduled for publication in Vol. 85 (3) 2022

Author(s) A. Vervaecke 1, S. van Ierssel 2, G. Vissers 3, E. Macken 1, B. Op de Beeck 4, T. Tondu 3, F. Thiessen 3, S. Francque 1, T. Steinhauser 1
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(1) Department of Gastroenterology and Hepatology, Antwerp University Hospital, Antwerp, Belgium
(2) Department of General Internal Medicine, Infectious Diseases and Tropical Medicine, Antwerp University Hospital, Antwerp, Belgium
(3) Department of Plastic and Reconstructive Surgery, Antwerp University Hospital, Antwerp, Belgium
(4) Department of Radiology, Antwerp University Hospital, Antwerp, Belgium

Acute pancreatitis can be complicated with necrosis of the pancreatic or peripancreatic tissue. This necrosis can become liquified and form a well-defined wall (walled-off necrosis or WON) and can become infected and form abscesses. Necrotizing soft tissue infections are rare infections of the deep tissue and subcutaneous fat and are mostly caused by trauma or perforated visceral organs. They can, however, rarely be caused by infected retroperitoneal collections. To date only 3 case reports have been published of a necrotizing soft tissue infection complicating a necrotizing pancreatitis. Both acute, complicated pancreatitis and necrotizing soft tissue infections carry a high mortality and morbidity rate with surgery being the mainstay therapy for the latter, often leaving the patient disfigured. We report the case of a 62-year-old man presenting to the emergency department with a painful and erythematous rash of the upper leg as complication of an acute necrotizing pancreatitis.

Keywords: Necrotizing fasciitis, necrotizing soft tissue infection, necrotizing pancreatitis, acute pancreatitis, complications
The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 35833907