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A rare case of paraneoplastic myositis associated with neuroendocrine carcinoma of the pancreas

Ahead of print available from 21/06/2022
These articles are scheduled for publication in Vol. 85 (4) 2022

Author(s) F. Decraene 1, F. Van De Mierop 1
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(1) Department of Gastroenterology, GZA Sint-Augustinus, Wilrijk, Belgium

Pancreatic cancer is only rarely associated with myopathy. We present a case of a 69-year-old male with recently diagnosed pancreatic cancer, who presented himself with a paraneoplastic myositis of both legs. MRI and EMG contributed to this diagnosis. Treatment was started with high dose corticosteroids followed by urgent laparoscopic pancreaticoduodenectomy. Postoperatively there was a rapid normalisation of the creatinine kinase levels with gradual increase of the muscle strength. The anatomopathology of the biopsy specimen showed a large cell neuroendocrine carcinoma. Paraneoplastic myositis associated with pancreatic cancer may be treated successfully with cancer specific treatment.

Keywords: pancreatic cancer, myositis, paraneoplastic syndrome, pancreaticoduodenectomy
© Acta Gastro-Enterologica Belgica.