Does endoscopic submucosal dissection have its place in the treatment of patients with gastric mucosa associated lymphoid tissue lymphoma localized disease after eradication?

Mucosa associated lymphoid tissue (MALT) lym- phoma, one of the B-cell non-Hodgkin’s lymphoma, always occurs in the extranodal margin zone. Gastric MALT lymphoma, has attracted attention because of its relationship with Helicobacter pylori (H. pylori). H. pylori eradication was considered as the first-line treatment regardless of stages and H. pylori status in the latest review (1). As for patients with localized disease who failed response after H. pylori eradication, radiotherapy was suggested, but is there a place for endoscopic treatment in such patients remains open to debate.