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Volume 83 - 2020 - Fasc.3 - Editorial

The changing landscape of hepatology and gastroenterology

The world is changing... the landscape of gastro- enterology and hepatology too. First, scientific knowledge is evolving. The complex mechanisms that explain liver and digestive diseases are becoming better and better characterized. In the previous issue of Acta Gastro-Enterologica Belgica, for example, we discovered the role of angiogenesis in non- alcoholic steatohepatitis (1), one of the most common liver diseases (2) without drug treatment available to date (3). In another interesting manuscript of this issue, the molecular characterization of hepatocellular carcinoma (or rather hepatocellular carcinomas) was summarized (4), suggesting therapeutic interventions tailored to individual patient’s profile in the future. In this issue, in the same vein, you will discover original manuscripts evaluating genetic virulence factors of Helicobacter pylori leading to specific gastro-intestinal manifestations (5), non-invasive tests that now frequently supplant liver biopsy in the context of chronic viral hepatitis B (6) as well as a case report on a rare digestive toxicity of immunotherapy (7).