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A single-centre analysis of post-colonoscopy colorectal cancer

Journal Volume 84 - 2021
Issue Fasc.3 - Original articles
Author(s) R. Aerts 1, C. Severi 2, G. Van Roey 3, R. Harlet 3, M. T’Syen 3, C. Claessens 3, S. Van Gool 3, C. Croonen 3, J. Janssens 3
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PAGES 401-405
(1) Department of Internal Medicine, University Hospitals Leuven, Leuven, Belgium
(2) Department of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium
(3) Department of Gastroenterology, AZ Turnhout, Turnhout, Belgium

Patients and methods: A prospective registration of patients with colorectal cancer and a colonoscopy within the last 10 years. We tried to classify these post-colonoscopy colorectal cancers (PCCRCs) by most reasonable explanation and into subcategories suggested by the World Endoscopy Organization (WEO) and calculated the unadjusted PCCRC rate.

Results: 47 PCCRCs were identified. The average age at diagnosis of PCCRC was 73 years. PCCRCs were more located in the right colon with a higher percentage of MSI-positive and B-RAF mutated tumours. The average period between index colonoscopy and diagnosis of PCCRC was 4.2 years. Sixty-eight % of all PCCRCs could be explained by procedural factors. The mean PCCRC-3y of our department was 2.46%.

Conclusions: The data of our centre are in line with the data of the literature from which can be concluded that most postcolonoscopy colorectal cancers are preventable. The PCCRC-3y is an important quality measure for screening colonoscopy. Ideally all centres involved in the population screening should measure the PCCRC-3 y annually, with cooperation of the cancer registry and reimbursement data provided by the Intermutualistic Agency (IMA).

Keywords: colonoscopy, screening, interval.

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 34599562