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Regression of multiple hepatocellular adenomas after cessation of oral contraceptive pills: a case report and review of the current literature

Journal Volume 84 - 2021
Issue Fasc.3 - Case reports
Author(s) G. Moors 1, H. Poels 1 2, V. Vandecaveye 3, T. Roskams 4, C. Verslype 1
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Full Article
PAGES 505-508
(1) Department of Digestive Oncology, University Hospitals Leuven, Belgium
(2) Department of Gastroenterology, Heilig Hart Ziekenhuis Lier, Belgium
(3) Department of Radiology, University Hospitals Leuven, Belgium
(4) Department of Pathology, University Hospitals Leuven, Belgium

Hepatocellular adenoma (HCA) is an uncommon benign liver neoplasm usually solitary and identified incidentally on imaging. We report a case of a 50-year old female who was diagnosed with multiple hepatic adenomas of the inflammatory subtype. After discontinuation of oral contraception a decrease of both the number and size of the liver lesions was seen on magnetic resonance imaging (MRI) without the need of further intervention. The major challenge in the clinical management of patients with multiple HCAs resides in the risk assessment for future complications. In the case of multiple HCAs subtype seemed to be more relevant than the actual number of lesions. Because little is known about the natural evolution in patients with multiple HCAs, we performed a review of the current literature with focus on the different subtypes and their clinical relevance.

Keywords: hepatic adenomatosis, oral contraception, conservative management.

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 34599577