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Chronic intestinal pseudo-obstruction: a case report with review of the literature and practical guidance for the clinician

Journal Volume 85 - 2022
Issue Fasc.1 - Reviews
Author(s) S. De Meulder 1, T. Vanuytsel 2
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Full Article
PAGES 85-93
(1) University Hospital, Department of Gastroenterology and Hepatology, Gasthuisberg, Leuven, Belgium
(2) University Hospital, Department of Gastroenterology and Hepatology, Leuven Intestinal Failure and Transplantation (LIFT). Gasthuisberg, Leuven, Belgium

Chronic Intestinal Pseudo-obstruction (CIPO) is a rare but debilitating and severe form of gastrointestinal dysmotility. The diagnosis is often made very late in the disease course due to its rarity and complexity. Treatment is mainly supportive, as there is no definitive cure. Pharmacologic therapy comprises prokinetics, antibiotics for bacterial overgrowth and pain management. Pain can also be alleviated with intestinal decompression in selected cases. Beside the pharmacologic therapy, nutrition and fluid replacement play a key role. Rarely, intestinal transplantation is necessary in patients with CIPO and intestinal failure. In this review, we describe an advanced CIPO case and provide an update of the clinical and diagnostic features and current management strategies. The goal of our review is to raise awareness around CIPO and to give practical guidance for the clinician.

Keywords: intestinal obstruction, CIPO, management..

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 35304998