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Esophageal Melanocytosis: report of two cases and review of a rare and misunderstood entity

Journal Volume 85 - 2022
Issue Fasc.2 - Case series
Author(s) A. Dubail 1 2 #, H. Dano 1 #, N. de Suray 3, H. Hassaini 3, A. Jouret-Mourin 2
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Full Article
PAGES 390-392
(1) Department of Pathology, Cliniques universitaires Saint-Luc, Université catholique de Louvain (UCLouvain), Brussels, Belgium
(2) Department of Pathology, Institut de Pathologie et de Génétique, Gosselies, Belgium.
(3) Department of Gastroenterology, Grand Hopital de Charleroi, Charleroi, Belgium
(#) Contributed equally

Esophageal melanocytosis (EM) is a rare entity, which is characterized by a non-atypical melanocytic proliferation and melanin deposits in the esophageal mucosa. The confusion between the terms of melanosis and melanocytosis in the literature, the rarity of this lesion (less than 50 cases reported in the literature), its uncertain pathobiological course and the lack of experience of pathologists and gastroenterologists prompt us to draw the attention to this particular entity by reporting two cases and reviewing the literature. Magnifying endoscopy to observe intensive melanin accumulation followed by a biopsy are key for the diagnosis.

Keywords: melanocytosis, pseudomelanosis, melanocytic lesion, esophagus, melanosis..

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 35709783