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Biliary papillomatosis

Journal Volume 86 - 2023
Issue Fasc.3 - Case series
Author(s) F. Gelders 1 2, M. Struyve 1, H. van Malenstein 2
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Full Article
PAGES 483-485
(1) Department of Gastroenterology and Hepatology, Ziekenhuis Oost-Limburg (ZOL), Genk, Belgium
(2) Department of Gastroenterology and Hepatology, University Hospitals Gasthuisberg, Leuven, Belgium

Biliary papillomatosis (BP) is a rare disorder of the biliary tract characterized by the presence of multiple papillary adenomas spread along the biliary tree. Although benign, it carries a significant risk of malignant transformation. Due to low sensitivity and specificity of conventional radiologic modalities, the diagnosis as well as estimation of disease extent is difficult. Endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreaticography (ERCP) are superior although direct peroral cholangioscopy (POC) is currently the most accurate diagnostic method. Mainly because it provides more detailed information and makes targeted histological diagnosis possible. The treatment of biliary papillomatosis consists of surgical resection, liver transplantation (LT) or a combination of both. Unfortunately, the recurrence rate after radical surgery without LT remains high due to the diffuse distribution of the disease.

Keywords: Biliary papillomatosis, endoscopic ultrasound, endoscopic retrograde cholangiography, cholangioscopy, liver transplantation.

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 37814564