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Fatal acute pulmonary embolism following endoscopic cyanoacrylate injection for gastric fundal varices

Journal Volume 87 - 2024
Issue Fasc.4 - Case reports
Author(s) C. Harth 1, P. De Mulder 2, S. Raevens 3, K. Ferdinande 3, P. Hindryckx 3, A. Geerts 3, H. Van Vlierberghe 3, P. Vanlangenhove 1, X. Verhelst 3
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PAGES 531-534
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DOI10.51821/87.4.13020
Affiliations:
(1) Department of Vascular and Interventional Radiology, Ghent University Hospital , Ghent, Belgium
(2) Department of Internal Medicine, VITAZ Sint Niklaas, Sint-Niklaas, Belgium
(3) Department of gastroenterology, Ghent University Hospital, Ghent, Belgium

Acute gastric variceal bleeding is a rare but serious complication of portal hypertension. Initial therapy for bleeding gastric varices focuses on acute hemostasis. In this regard, endoscopic cyanoacrylate injection (ECI) is the first-line approach. Cyanoacrylate diluted with Lipiodol acts as a tissue adhesive that polymerizes on contact with blood. Glue-induced pulmonary embolism is a very rare but severe complication of ECI. This paper describes a case of fatal glue pulmonary embolism during ECI for prevention of bleeding from gastric fundal varices in a patient with polycythemia vera and the presence of portosystemic shunts.

Keywords: endoscopic sclerotherapy injection, gastric varices, pulmonary embolis, polycythemia vera.

© Acta Gastro-Enterologica Belgica.
PMID 39745042