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Post-transplantation lymphoproliferative disorder (PTLD) with rectal involvement

Journal Volume 88 - 2025
Issue Fasc.2 - Clinical images
Author(s) K. Mombaerts 1, J-B. Zeevaert 2, B. Feytmans 2, M. Vivario 3
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PAGES 215-216
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DOI10.51821/88.1.13641
Affiliations:
(1) Gastroenterology Unit, Clinique MontLégia, CHC Groupe Santé, Liège, Belgium
(2) Gastroenterology Unit, CHR Verviers, East Belgium, Verviers, Belgium
(3) Anatomopathology Unit, CHR Verviers, East Belgium, Verviers, Belgium

We report the case of a 72-year-old man, with a history of kidney transplantation eight years ago, who consulted for rectal bleeding without other symptoms. The patient underwent a rectosigmoidoscopy and this examination showed a 9mm rounded ulcerated rectal lesion classified as such: Paris IIc, JNET III, KUDO V (Figure 1). The optical diagnosis suggest an adenocarcinoma with high risk of invasion. The patient then performed an ultrasound endoscopy confirming a hypoechoic lesion involving the avoid difficulties related to post-biopsy fibrosis that complicates the resection (Figure 1). The anatomopathological results do not support the diagnosis of an adenocarcinoma. What is your diagnosis?

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