Correlating Quality of Life with Point-of-Care Intestinal Ultrasound in Inflammatory Bowel Disease (CUALITY Study)
| Journal | Volume 88 - 2025 |
| Issue | Fasc.4 - Original articles |
| Author(s) | V. Parra Izquierdo 1 2 3 4, K. Ernest Suarez 5, M. Argollo 6, J. Frías-Ordoñez 3, G. Orduz 3, F. Puentes Manosalva 7, M. Vargas 8, S. Cubillos 3, E. Eggermont 1 2, B. Verstockt 1 2 |
| Full article |
 PAGES 314-322 VIEW FREE PDF |
| DOI | 10.51821/88.4.14457 |
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Affiliations: (1) KU Leuven Department of Chronic Diseases and Metabolism, Translational Research Center for Gastrointestinal Disorders TARGID, Leuven, Belgium
(2) Department of Gastroenterology and Hepatology, University Hospitals Leuven, KU Leuven, Leuven, Belgium (3) Hospital Internacional de Colombia, Center of Excellence in Inflammatory Bowel Disease, Bucaramanga, Colombia (4) Cellular and Molecular Immunology Group–InmuBo, Universidad El Bosque, Bogota, Colombia (5) School of Medicine- Universidad de Costa Rica, San Jose, Costa Rica (6) Universidad Federal de São Paulo, Gastroenterology, Sao Paulo, Brazil (7) Unión de Cirujanos. ODO. Zentria Salud - Universidad de Caldas, Manizales, Colombia (8) Gastrokids SAS, Pereira, Colombia |
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Background: Inflammatory bowel disease (IBD) impacts patients’ quality of life (QoL), and hence, there is a need to assess this through patient-reported outcomes (PRO). Intestinal ultrasound (IUS) is a non-invasive tool for monitoring IBD activity, but little is known about its correlation with PRO. This study explored the cross-sectional relationship between PRO, assessed by the IBD Questionnaire-32 (IBDQ-32), and IUS parameters in patients with ulcerative colitis (UC). Methods: This prospective study included 37 Colombian patients with UC. IUS parameters such as bowel wall thickness (BWT), colour Doppler signal (CDS), and mesenteric fat hypertrophy were assessed, followed by IBDQ-32 completion. Two IUS-experienced gastroenterologists, blinded to the IBDQ- 32, performed the assessments. Results: In UC, lower IBDQ-32 scores were significantly correlated with increased BWT (p=0.050), presence of CDS (p=0.022), higher Limberg score (p=0.032), and mesenteric fat hypertrophy (p=0.040). The gastrointestinal and systemic symptom dimensions of the IBDQ-32 showed significant correlations with both BWT (p=0.013 and p=0.013) and CDS (p=0.002 and p=0.003), respectively. Conclusions: In UC, IUS parameters are significantly correlated with quality of life, reinforcing the value of IUS as a point-of-care tool. Keywords: intestinal ultrasound, ulcerative colitis, quality of life. |
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© Acta Gastro-Enterologica Belgica. PMID 41493319 |