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Evaluation of the clinical course and prognostic indices of acute pancreatitis in elderly patients : a prospective study

Journal Volume 83 - 2020
Issue Fasc.3 - Original articles
Author(s) H. Satis 1, N. Kayahan 2, Z.G. Sargin 3, A. Karatas 3, D. Çeliker 4
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Full Article
PAGES 413-417
(1) Department of internal medicine, Gazi University Medical School, Besevler, Ankara
(2) Department of internal medicine, Gulhane Education and Research Hospital,Yenimahalle, Ankara
(3) Department of gastroenterology, Gazi University Medical School, Besevler, Ankara
(4) Department of Public Health and Biostatistics Department Gazi University Medical School Besvevler, Ankara, Turkey

Background and aim: Acute pancreatitis (AP) is a life- threatening condition across all age groups. In this study, it was aimed to investigate the severity of the disease and associated mortality in the geriatric population.

Methodology: This single-center, prospective study elderly (≥65 years of age) and younger (18-65 years of age) total 147 patients with AP are enrolled To diagnose and asses the severity of AP Atlanta classification was used. Baseline and 12-months follow-up data included Ranson, Imrie, BISAP, APACHE-II, SOFA, Modified Marshall, Balthazar, and Computed Tomography Severity Index (CTSI) as prognostic tools.

Results: 6 (15%) patiens in elderly and 5 (6,7%) patients in non elderly group had modarete-severe AP . Patients were followed up 1 year and during this time no systemic complications were seen , 8 (20%) patients in elderly group and 10 (13,6%) patients in younger group had local complications. 1 patients in elderly and 2 patients in non elderly group had acute necrotic collection whereas 1 patient developed walled of necrosis in non elderly group. The elderly patients with any of the following index characteristics would not be expected to have a mild disease course: Imrie score ≥ 3, BISAP score ≥ 3, APACHE-II ≥ 11, CRP ≥ 195 mg/dl

Conclusions: AP caused a prolonged hospitalization in the elderly compared to younger patients but its severity and clinical outcomes were not different in the two groups.

Keywords: Acute pancreatitis, APACHE, Blood urea nitrogen, C-reactive protein, elderly patients, prognosis.

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 33094588