Isolated amyloidosis of the gastro-intestinal tract
Journal | Volume 85 - 2022 |
Issue | Fasc.1 - Reviews |
Author(s) | S. Smeets 1, F. Dedeurwaerdere 2, E. Thomaere 3, B. Houthoofd 3, L. D’Hulst 4, P. Wilmes 5, F. Offner 6, S. De Coninck 7 |
Full article |
PAGES 80-84 VIEW FREE PDF |
DOI | 10.51821/85.1.8499 |
Affiliations: (1) Gastroenterologist in training, University hospital of Ghent
(2) Department of anatomopathology Sint-Andries hospital Tielt (3) Department of radiology Sint-Andries hospital Tielt (4) Department of nuclear medicine Sint-Andries hospital Tielt (5) Department of oncology Sint-Andries hospital Tielt (6) Department of hematology University hospital Ghent (7) Department of gastroenterology Sint-Andries hospital Tielt |
Amyloidosis is a very rare condition, which, due to its rarity, is often missed or diagnosed in an advanced stage of the disease, causing significant morbidity and mortality. In this review we describe the existing types of amyloidosis focusing on the gastro-intestinal tract. Amyloidosis occurs when abnormal protein fibrils (amyloid) deposit in the muscularis mucosae. This can cause an array of symptoms ranging from (in order of occurrence): gastro-intestinal bleeding, heartburn, unintentional weight loss, early satiety, constipation, diarrhea, nausea, vomiting and fecal incontinence (1). Treatment is focused on the underlying condition (if any) causing the production and deposition of the abnormal fibrils, in combination of symptomatic treatment. Keywords: Amyloidosis, gastro-intestinal amyloid deposition. |
© Acta Gastro-Enterologica Belgica. PMID 35304997 |