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Stauffer syndrome : a rare paraneoplastic complication of renal cell carcinoma to be kept in mind. Case report and literature survey

Journal Volume 87 - 2024
Issue Fasc.1 - Case reports
Author(s) M. Deliège 1, B. Bastens 1, G. Matus 2, N. Blétard 3, G. Houbiers 1 2, A. Courtois 2, C. Focan 2
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PAGES 40-43
(1) Gastroenterology department, Clinique CHC MontLegia, Liège, Belgium
(2) Onco-hematology department, Clinique CHC-MontLegia, Liège, Belgium
(3) Anatomo-pathology department, Clinique CHC-MontLegia, Liège, Belgium

The authors report the case of a 74-years-old woman treated by immunotherapy for a metastatic renal cell carcinoma and having developed an important cholestasis with thrombocytosis, increased CRP, leucocytosis and hypoalbuminemia. Liver remained free of metastases at medical imaging. The diagnosis of a Stauffer syndrome was confirmed by the hepatic biopsy. A complete response of liver disorders was obtained after nephrectomy. From literature survey, Stauffer syndrome should be kept in mind in cancer patients, especially those suffering from a renal cell carcinoma, presenting with cholestasis with no underlying cause.

Keywords: Stauffer syndrome, renal cell carcinoma.

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 38431790