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Acute grade IV toxic hepatitis due to the e-cigarette

Journal Volume 87 - 2024
Issue Fasc.1 - Case reports
Author(s) G. Van Roey 1, W. Goos 1, C. Claessens 1, A. Hoorens 2, W. Verlinden 3, J. Schouten 3
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PAGES 44-47
(1) Department of Gastroenterology, AZ Turnhout, Turnhout, Belgium
(2) Department of Pathology, University Hospital Ghent, Ghent, Belgium
(3) Department of Gastroenterology, VITAZ, St Niklaas, Belgium

A 46-year-old woman presented at the emergency department because of acute hepatitis with jaundice. After hepatological work-up including liver biopsy, drug induced liver disease (DILI) was suspected. Patient recovered completely within a few months. One year later she presented again with jaundice due to acute hepatitis. Vaping was the only agent that could be identified as causative agent for DILI. After VAPING cessation, the hepatitis resolved completely. Calculated RUCAM score was 10, making the diagnosis of toxic hepatitis very likely. During follow-up liver tests remained normal. This is the first report of severe DILI secondary to the use of e-cigarettes. In future vaping can be included in the differential diagnosis of DILI.

Keywords: case report, DILI, vaping, e-cigarette.

The authors declare that they have no conflict of interest.
© Acta Gastro-Enterologica Belgica.
PMID 38431791