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Reactivation of Resolved Hepatitis B virus Infection before the Relapse of Lymphoma : Immunosuppressive effect of the Lymphoproliferative disorders ?

Journal Volume 79 - 2016
Issue Fasc.1 - Letters
Author(s) Huseyin Savas Gokturk, Gulhan Kanat Unler, Bahar Gokturk
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(1) Department of Gastroenterology, Baskent University Faculty of Medicine, Konya, Turkey ; (2) Department of Pediatric Allergy and Immunology, Konya Training and Research Hospital, Konya, Turkey..

Hepatitis B virus (HBV) infection is a heterogeneous disease with distinct phases determined mainly by the interaction between virus replication and host immune response. HBV reactivation can occur spontaneously, developing resistance to antiviral treatment while the patient is undergoing treatment, after cessation of antiviral drugs, or be triggered by immunosuppressive drugs and chemotherapy. HBV reactivation can be severe and sometimes fatal because of liver failure. Here we report a patient with resolved HBV infection who presented with reactivation before being diagnosed with a relapse of non-Hodgkin lymphoma. (Acta gastro-enterol. belg., 2016, 79, 63-64).

© Acta Gastro-Enterologica Belgica.
PMID 26852769