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Eosinophilic esophagitis

Journal Volume 76 - 2013
Issue Fasc.4 - Case series
Author(s) M.A. Bordea, O. Moşteanu, T.A. Pop, D. Gheban, G. Samaşca, N. Miu
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(1) Pediatrics Clinics II Emergency Hospital for Children, Cluj-Napoca, Romania ; (2) Department of Clinical Gastroenterology IV, Regional Institute for Gastroenterology and Hepatology Prof. Dr. “O. Fodor”, Cluj-Napoca, Romania ; (3) Department of Medical Clinic III ; (4) Department of Morphology ; (5) Department of Immunology ; (6) Department of Pediatrics II ; “Iuliu Hatieganu” University of Medicine and Pharmacy, Cluj-Napoca, Romania.

Eosinophilic esophagitis is a chronic, immune-mediated disor- der, isolated to the esophagus. Current theory suggests that the former may be caused by cell-mediated food hypersensitivity or may be a subset of eosinophilic gastrointestinal disease, an auto- immune disorder. During the last decade, the increasing prevalence of Eoe has been recognized in pediatric populations. Reports -support-the-efficacy-of-dietary-restriction-or-corticosteroid-therapy. Aditional research is needed to determine etiology, allow earlier clinical recognition and improve treatment. Because no single symptom,-endoscopic-finding-or-histopathologic-feature-is-pathog- nomonic, the diagnosis can frequently be challenging. The current article reviews the possible etiology, clinical presentation, diagno- sis, and treatment of this disorder, which has been called not only allergic esophagitis (which may be the most important cause), but also eosinophilic esophagitis, primary eosinophilic esophagitis, and idiopathic eosinophilic esophagitis. (Acta gastroenterol. belg., 2013, 76, 407-412).

© Acta Gastro-Enterologica Belgica.
PMID 24592544