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Volume 78 - 2015 - Fasc.1 - Reviews

Distal intestinal obstruction in CF patients

Distal intestinal obstruction syndrome (DIOS) - the incomplete of complete intestinal obstruction by intestinal contents in the ter- minal ileum and proximal colon- is frequently seen in cystic fibrosis (CF) patients. Diagnosis is based on suggestive symptoms of ab- dominal pain in the right lower quadrant, a palpable mass on ex- amination and signs of obstruction on plain radiography. Treat- ment consists of intensive laxative treatment with oral laxatives and enemas. Surgery only serves as the last resort for patients not responding to medical therapy, because of the well-known high rate of peri- and postoperative morbidity of surgery in CF patients. In this article we present 3 cases of DIOS, followed by a review of the relevant literature. (Acta gastroenterol. belg., 2015, 78, 49-52).

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Ecstasy induced acute hepatic failure. Case reports

3,4-methylenedioxymethamphetamine (MDMA), an amphet- amine derivative known as ecstasy, has stimulating and hallucino- genic properties. It has become a substance that is widely used es- pecially by young people. Hepatotoxicity is one of the rare side effects of this substance and can be fatal. Ecstasy-induced fulmi- nant hepatitis has been reported in case reports. The clinical course and the prognosis of the cases may differ. In this article, two cases in whom ecstasy-induced fulminant hepatic failure had developed and who were treated with liver transplantation, and one case which recovered with treatment, have been presented. (Acta gastro- enterol. belg., 2015, 78, 53-55).

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